Annotation Detail

Information
Associated Genes
SHOC2
Associated Variants
SHOC2 p.Ser2Gly (p.S2G) ( ENST00000369452.9, ENST00000451838.2, ENST00000265277.10, ENST00000685059.1, ENST00000688928.1, ENST00000689118.1, ENST00000689300.1, ENST00000689997.1, ENST00000691369.1, ENST00000691441.1, ENST00000691903.1, ENST00000692776.1 )
SHOC2 p.Ser2Gly (p.S2G) ( ENST00000265277.10, ENST00000369452.9, ENST00000451838.2, ENST00000685059.1, ENST00000688928.1, ENST00000689118.1, ENST00000689300.1, ENST00000689997.1, ENST00000691369.1, ENST00000691441.1, ENST00000691903.1, ENST00000692776.1 )
Associated Disease
Noonan-Like Syndrome With Loose Anagen Hair
Source Database
DisGeNET
Description
Noonan-like syndrome with loose anagen hair (NS/LAH; OMIM 607721) due to a missense mutation c.4A>G in SHOC2 predicting p.Ser2Gly has been described recently.
Pubmed
24458596
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Year of publication
2013
Drugs