Annotation Detail

Information
Associated Genes
FLT3
Associated Variants
FLT3 MUTATION
FLT3 MUTATION
Associated Disease
Neoplasm, Residual
Source Database
DisGeNET
Description
Although pretreatment covariates such as cytogenetics, monosomal karyotype, relapsed or refractory rather than newly diagnosed AML, and FLT3 internal tandem duplication were associated with relapse, their prognostic effect was much lower once MRD and response were taken into account, the univariable statistical effect of which was not materially affected by inclusion of pretreatment covariates.
Pubmed
25732155
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0116059871509965
Drugs