Annotation Detail

Information
Associated Genes
PIK3CG
Associated Variants
PIK3CG MUTATION
PIK3CG MUTATION
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Common molecular drivers of lung cancer are mutations in receptor tyrosine kinases (RTKs) leading to activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pro-growth, pro-survival signaling pathways.
Pubmed
25524703
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00895758177865001
Drugs