Annotation Detail
Information
- Associated Genes
- NLRP1
- Associated Variants
-
rs2670660
(
ENST00000576905.6 )
rs2670660 ( ENST00000576905.6 ) - Associated Disease
- Malignant neoplasm of prostate
- Source Database
- DisGeNET
- Description
- Expression of snpRNAs in human and mouse cells markedly affects cellular behavior and induces allele-specific clinically relevant phenotypic changes: NLRP1-locus snpRNAs rs2670660 exert regulatory effects on monocyte/macrophage transdifferentiation, induce prostate cancer (PC) susceptibility snpRNAs and transform low-malignancy hormone-dependent human PC cells into highly malignant androgen-independent PC.
- Pubmed
- 22067658
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs