Annotation Detail

Information
Associated Genes
MAP2K1
Associated Variants
MAP2K1 MUTATION
MAP2K1 MUTATION
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
MEK1 mutations define a distinct subset of lung cancers (∼1%) with potential sensitivity to MEK inhibitors.
Pubmed
25351745
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
14
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00508145069940506
Drugs