Annotation Detail

Information
Associated Genes
FDFT1
Associated Variants
FDFT1 c.879+739A>C ( ENST00000220584.9, ENST00000443614.6, ENST00000525900.5, ENST00000525954.5, ENST00000528643.5, ENST00000528812.5, ENST00000530337.6, ENST00000530664.5, ENST00000615631.4, ENST00000622850.3 )
FDFT1 c.879+739A>G ( ENST00000530664.5, ENST00000528643.5, ENST00000525954.5, ENST00000443614.6, ENST00000525900.5, ENST00000528812.5, ENST00000220584.9, ENST00000530337.6, ENST00000615631.4, ENST00000622850.3 )
FDFT1 c.879+739A>C ( ENST00000220584.9, ENST00000443614.6, ENST00000525900.5, ENST00000525954.5, ENST00000528643.5, ENST00000528812.5, ENST00000530337.6, ENST00000530664.5, ENST00000615631.4, ENST00000622850.3 )
FDFT1 c.879+739A>G ( ENST00000220584.9, ENST00000443614.6, ENST00000525900.5, ENST00000525954.5, ENST00000528643.5, ENST00000528812.5, ENST00000530337.6, ENST00000530664.5, ENST00000615631.4, ENST00000622850.3 )
Associated Disease
Non-alcoholic Fatty Liver Disease
Source Database
DisGeNET
Description
Recently, a polymorphism of single nucleotide polymorphism SNP rs2645424 of farnesyl diphosphate farnesyl transferase 1 (FDFT1) was identified in NAFLD/NASH as a possible causal link to steatosis and fibrosis progression.
Pubmed
23870067
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00290991572276264
Year of publication
2013
Drugs