Annotation Detail

Information
Associated Genes
CYP1A1
Associated Variants
CYP1A1 c.-30+606G>T ( ENST00000564596.5, ENST00000395048.6, ENST00000567032.5, ENST00000395049.8, ENST00000379727.8, ENST00000617691.4 )
CYP1A1 c.-30+606G>T ( ENST00000379727.8, ENST00000395048.6, ENST00000395049.8, ENST00000564596.5, ENST00000567032.5, ENST00000617691.4 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Moreover, the association between CYP1A1 rs2606345 genotype and lung cancer was significantly modified by intensity of cigarette smoking, suggesting an underlying dose-response mechanism.
Pubmed
19479063
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.123702141404929
Year of publication
2009
Drugs