Annotation Detail

Information
Associated Genes
CYP1A1
Associated Variants
CYP1A1 c.-30+606G>T ( ENST00000564596.5, ENST00000395048.6, ENST00000567032.5, ENST00000395049.8, ENST00000379727.8, ENST00000617691.4 )
CYP1A1 c.-30+606G>T ( ENST00000379727.8, ENST00000395048.6, ENST00000395049.8, ENST00000564596.5, ENST00000567032.5, ENST00000617691.4 )
Associated Disease
Depressive Symptoms
Source Database
DisGeNET
Description
Among Caucasian women, those with the CYP1A1 rs2606345 CC and AC genotypes had approximately 2-fold greater odds of having depressive symptoms than did those with the AA genotype (95% confidence intervals [CIs], 1.33 to 4.66 and 1.25 to 3.14, respectively).
Pubmed
16949393
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2006
Drugs