Annotation Detail

Information
Associated Genes
GSTM3
Associated Variants
GSTM3 MUTATION
GSTM3 MUTATION
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
The smokers with CYP1A1 Msp1 (wt/vt+vt/vt), CYP1A1 exon7 (Val/Val+Ile /Val), GSTM1 (-), GSTM3 (AB+BB), and GSTT1 (-) genotypes, respectively, are at elevated risk of lung cancer.
Pubmed
25040976
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.015830843104094
Drugs