Annotation Detail

Information
Associated Genes
HTR1A
Associated Variants
rs25531
HTR1A c.-1019G>C
rs25531
HTR1A c.-1019G>C
Associated Disease
Depressive Symptoms
Source Database
DisGeNET
Description
We examined the valine (Val) to methionine (Met) polymorphism in brain-derived neurotrophic factor (BDNF), serotonin 1A receptor (5HT1a-rs6295) polymorphism, and the serotonin transporter-linked polymorphic region (5HTTLPR) interaction with the rs25531 A to G single nucleotide polymorphism (5HTTLPR-rs25531) as predictors of depressive symptoms.
Pubmed
25781924
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Year of publication
2015
Drugs