Annotation Detail

Information
Associated Genes
SLC6A4
Associated Variants
rs25531
rs25531
Associated Disease
Mental Depression
Source Database
DisGeNET
Description
To further delineate the impact of 5-HTT gene variation on psychopathology in depression, in this analysis the influence of the 5-HTTLPR and the functionally closely related 5-HTT rs25531 was investigated in 340 Caucasian patients with a major depressive episode (DSM-IV) with particular attention to the subtype of depression (melancholic depression versus atypical depression) applying logistic regression models adjusted for age and gender.
Pubmed
18050262
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.154646514822083
Year of publication
2008
Drugs