Annotation Detail
Information
- Associated Genes
- SLC6A4
- Associated Variants
-
rs25531
rs25531 - Associated Disease
- Mental Depression
- Source Database
- DisGeNET
- Description
- The serotonin transporter (5-HTT) and the 5-HTTLPR/rs25531 polymorphisms in its gene (SLC6A4) have been associated with depression, increased stress-response, and brain structural alterations such as reduced hippocampal volumes.
- Pubmed
- 24862560
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.154646514822083
- Year of publication
- 2014
Drugs