Annotation Detail
Information
- Associated Genes
- PDGFRA
- Associated Variants
-
PDGFRA MUTATION
PDGFRA MUTATION - Associated Disease
- Fibrosis, Liver
- Source Database
- DisGeNET
- Description
- Studies elucidating PDGFRα signaling in processes ranging from profibrotic signaling, angiogenesis, and oxidative stress to epithelial-to-mesenchymal transition point toward PDGFRα as a potential therapeutic target in various hepatic pathologies, including hepatic fibrosis and liver cancer.
- Pubmed
- 25700367
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs