Annotation Detail

Information
Associated Genes
XRCC1
Associated Variants
XRCC1 MUTATION
XRCC1 MUTATION
XRCC1 p.Gln399Arg (p.Q399R) ( ENST00000262887.10, ENST00000543982.5 )
XRCC1 p.Gln399Arg (p.Q399R) ( ENST00000262887.10, ENST00000543982.5 )
Associated Disease
cervix carcinoma
Source Database
DisGeNET
Description
XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer.
Pubmed
16875718
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0129968722514521
Year of publication
2006
Drugs