Annotation Detail

Information
Associated Genes
HLA-E
Associated Variants
HLA-E MUTATION
HLA-E MUTATION
Associated Disease
Papillary thyroid carcinoma
Source Database
DisGeNET
Description
MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro.
Pubmed
25294906
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs