Annotation Detail

Information
Associated Genes
PTPN2
Associated Variants
rs2542151
PTPN2 c.69+7012T>C ( ENST00000309660.10, ENST00000327283.7, ENST00000353319.8, ENST00000591115.5, ENST00000645191.1, ENST00000646492.1 )
rs2542151
PTPN2 c.69+7012T>C ( ENST00000309660.10, ENST00000327283.7, ENST00000353319.8, ENST00000591115.5, ENST00000645191.1, ENST00000646492.1 )
Associated Disease
Inflammatory Bowel Diseases
Source Database
DisGeNET
Description
Genomic DNA from 2131 individuals of Caucasian origin (905 patients with CD, 318 patients with UC, and 908 healthy, unrelated controls) was analyzed for two SNPs in the PTPN2 region (rs2542151, rs7234029) for which associations with IBD were found in previous studies in other cohorts.
Pubmed
22457781
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.123995683211084
Year of publication
2012
Drugs