Annotation Detail
Information
- Associated Genes
- MOK
- Associated Variants
-
MOK MUTATION
MOK MUTATION - Associated Disease
- Anaplastic thyroid carcinoma
- Source Database
- DisGeNET
- Description
- Mechanistic investigations showed that S100A8 promotes ATC cell proliferation through an interaction with RAGE, which activates the p38, ERK1/2 and JNK signaling pathways in the tumor cells.
- Pubmed
- 25423568
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs