Annotation Detail

Information
Associated Genes
FGFR1
Associated Variants
FGFR1 MUTATION
FGFR1 MUTATION
Associated Disease
Gastrointestinal Stromal Tumors
Source Database
DisGeNET
Description
Here, we report that ligands from the FGF family reduced the effectiveness of imatinib in GIST cells, and FGF2 and FGFR1 are highly expressed in all primary GIST samples examined.
Pubmed
25673643
Section of the abstract supporting the evidence
UNLABELLED
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs