Annotation Detail

Information
Associated Genes
PDGFRA
Associated Variants
PDGFRA MUTATION
PDGFRA MUTATION
Associated Disease
Gastrointestinal Stromal Tumors
Source Database
DisGeNET
Description
Approximately 7.5% of gastric gastrointestinal stromal tumors are SDH-deficient and not driven by KIT/PDGFRA mutations, as are most other GISTs.
Pubmed
24886695
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT
DisGENET score for the Gene Disease association
0.615647293561465
Drugs