Annotation Detail
Information
- Associated Genes
- RAF1
- Associated Variants
-
RAF1 MUTATION
RAF1 MUTATION - Associated Disease
- pancreatic carcinoma
- Source Database
- DisGeNET
- Description
- Activating point mutations in the KRAS oncogene are prevalent in pancreatic cancer and result in the stimulation of several pathways including the RAF-mitogen-activated protein kinase pathway and the phosphoinositide 3-kinase pathway.
- Pubmed
- 24445769
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
Drugs