Annotation Detail

Information
Associated Genes
TPM1
Associated Variants
TPM1 p.Asp217Asn (p.D217N) ( ENST00000559556.5, ENST00000559397.6, ENST00000560970.6, ENST00000561266.6, ENST00000357980.9, ENST00000358278.7, ENST00000317516.12, ENST00000560615.6, ENST00000334895.10, ENST00000560959.5, ENST00000403994.9, ENST00000558910.3, ENST00000559281.6, ENST00000288398.10, ENST00000404484.9, ENST00000267996.11, ENST00000651704.1, ENST00000714013.1, ENST00000651577.1, ENST00000714014.1, ENST00000714017.1 )
TPM1 p.Asp217Asn (p.D217N) ( ENST00000267996.11, ENST00000288398.10, ENST00000317516.12, ENST00000334895.10, ENST00000357980.9, ENST00000358278.7, ENST00000403994.9, ENST00000404484.9, ENST00000558910.3, ENST00000559281.6, ENST00000559397.6, ENST00000559556.5, ENST00000560615.6, ENST00000560959.5, ENST00000560970.6, ENST00000561266.6, ENST00000651577.1, ENST00000651704.1, ENST00000714013.1, ENST00000714014.1, ENST00000714017.1 )
Associated Disease
Precursor B-cell lymphoblastic leukemia
Source Database
DisGeNET
Description
Significance of plasma levels of N-terminal Pro-B-type natriuretic peptide on left ventricular remodeling in non-obstructive hypertrophic cardiomyopathy attributable to the Asp175Asn mutation in the alpha-tropomyosin gene.
Pubmed
18394456
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2008
Drugs