Annotation Detail

Information
Associated Genes
MAPT
Associated Variants
MAPT c.-17-19975G>A ( ENST00000446361.7, ENST00000262410.10, ENST00000344290.10, ENST00000535772.6, ENST00000334239.12, ENST00000420682.7, ENST00000680674.1, ENST00000351559.10 )
MAPT c.1999-6612A>G ( ENST00000344290.10, ENST00000574436.5, ENST00000535772.6, ENST00000262410.10, ENST00000415613.6, ENST00000446361.7, ENST00000571987.5, ENST00000431008.7, ENST00000351559.10, ENST00000334239.12, ENST00000420682.7, ENST00000680674.1 )
MAPT c.-17-19975G>A ( ENST00000262410.10, ENST00000334239.12, ENST00000344290.10, ENST00000351559.10, ENST00000420682.7, ENST00000446361.7, ENST00000535772.6, ENST00000680674.1 )
MAPT c.1999-6612A>G ( ENST00000262410.10, ENST00000334239.12, ENST00000344290.10, ENST00000351559.10, ENST00000415613.6, ENST00000420682.7, ENST00000431008.7, ENST00000446361.7, ENST00000535772.6, ENST00000571987.5, ENST00000574436.5, ENST00000680674.1 )
Associated Disease
progressive supranuclear palsy
Source Database
DisGeNET
Description
[We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression.]
Pubmed
21685912
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.558157698507233
Year of publication
2011
Drugs