Annotation Detail

Information
Associated Genes
HLA-DPB1
Associated Variants
rs2395309
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
rs2395309
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 )
Associated Disease
hepatitis B
Source Database
DisGeNET
Description
By using logistic regression analysis, these two SNPs in the HLA-DPA1 and HLA-DPB1 genes were significantly associated with HBV infection in Han Chinese populations (P = 0.021∼3.36×10(-8) at rs2395309; P = 8.37×10(-3)∼2.68×10(-10) at rs9277535).
Pubmed
21904616
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.132334436375453
Year of publication
2011
Drugs