Annotation Detail
Information
- Associated Genes
- TET2
- Associated Variants
-
TET2 MUTATION
TET2 MUTATION - Associated Disease
- Mastocytosis, Systemic
- Source Database
- DisGeNET
- Description
- We exploit these findings to validate a combination treatment strategy targeting the epigenetic deregulation caused by loss of TET2 and the constitutively active KIT receptor for the treatment of patients with aggressive SM.
- Pubmed
- 24788138
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00453856695524446
Drugs