Annotation Detail
Information
- Associated Genes
- CYP2D6
- Associated Variants
-
SLCO1B1 p.Asn130Asp (p.N130D)
(
ENST00000256958.3 )
SLCO1B1 p.Val174Ala (p.V174A) ( ENST00000256958.3 )
SLCO1B1 p.Asn130Asp (p.N130D) ( ENST00000256958.3 )
SLCO1B1 p.Val174Ala (p.V174A) ( ENST00000256958.3 ) - Associated Disease
- Progesterone receptor positive tumor
- Source Database
- DisGeNET
- Description
- The aim of this study was to evaluate the association of CYP2D6*10 (c.100C>T and c.1039C>T), OATP1B1 A388G, and OATP1B1 T521C polymorphisms with overall survival (OS) for hormone receptor (estrogen receptor or progesterone receptor)-positive tumors (ER+/PR+) breast cancer patients after adjuvant tamoxifen (TAM) therapy.
- Pubmed
- 25701109
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2015
Drugs