Annotation Detail

Information
Associated Genes
APOE
Associated Variants
BMAL2 c.1477+176T>C ( ENST00000266503.10, ENST00000311001.9, ENST00000261178.9, ENST00000544915.5, ENST00000395901.6, ENST00000542388.1, ENST00000546179.5 )
BMAL2 c.1477+176T>C ( ENST00000261178.9, ENST00000266503.10, ENST00000311001.9, ENST00000395901.6, ENST00000542388.1, ENST00000544915.5, ENST00000546179.5 )
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
C carriers in BMAL2 gene rs2306074 T/C are associated with a high susceptibility of AD among APOE ε 4 non-carriers but not among APOE ε 4 carriers in Chinese population.
Pubmed
24847962
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.44
Year of publication
2014
Drugs