Annotation Detail
Information
- Associated Genes
- KDR
- Associated Variants
-
EGF c.-382A>G
(
ENST00000265171.10,
ENST00000509793.5,
ENST00000652245.1 )
KDR c.659-24G>T ( ENST00000263923.5 )
KDR c.659-24G>A ( ENST00000263923.5 )
EGF c.-382A>G ( ENST00000265171.10, ENST00000509793.5, ENST00000652245.1 )
KDR c.659-24G>T ( ENST00000263923.5 )
KDR c.659-24G>A ( ENST00000263923.5 ) - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- Two additional SNPs, rs4444903 in EGF and rs2305949 in KDR, were associated with hypertension (allelic OR 1.57 [95 % CI 1.17-2.11], P = 0.0025; allelic OR 0.62 [95 % CI 0.42-0.93], P = 0.020, respectively) and closely linked to nearby functional variants.
- Pubmed
- 24558090
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0834527994669232
- Year of publication
- 2014
Drugs