Annotation Detail
Information
- Associated Genes
- TYK2
- Associated Variants
-
TYK2 p.Val362Phe (p.V362F)
(
ENST00000524462.5,
ENST00000525621.6,
ENST00000525976.6,
ENST00000531836.6,
ENST00000699360.1 )
TYK2 p.Val362Phe (p.V362F) ( ENST00000524462.5, ENST00000525621.6, ENST00000525976.6, ENST00000531836.6, ENST00000699360.1 ) - Associated Disease
- multiple sclerosis
- Source Database
- DisGeNET
- Description
- The highest association was at marker rs2304256 (odds ratio (OR) = 0.86; 95%CI = 0.82-0.90) in the TYK2 gene, which has previously been associated with systemic lupus erythematosus and multiple sclerosis.
- Pubmed
- 19966805
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.133192369253412
- Year of publication
- 2010
Drugs