Annotation Detail

Information
Associated Genes
HCN4
Associated Variants
HCN4 p.Asp553Asn (p.D553N) ( ENST00000261917.4 )
HCN4 p.Asp553Asn (p.D553N) ( ENST00000261917.4 )
Associated Disease
Sick sinus syndrome 2, autosomal dominant
Source Database
DisGeNET
Description
Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia.
Pubmed
15123648
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.36
Year of publication
2004
Drugs