Annotation Detail

Information
Associated Genes
GNB3
Associated Variants
GNB3 c.700-126G>A ( ENST00000229264.8, ENST00000422785.7, ENST00000435982.6 )
ADD1 p.Gly460Trp (p.G460W) ( ENST00000264758.11, ENST00000398129.5, ENST00000683351.1 )
GNB3 c.700-126G>A ( ENST00000229264.8, ENST00000435982.6, ENST00000422785.7 )
ADD1 p.Gly460Trp (p.G460W) ( ENST00000264758.11, ENST00000398129.5, ENST00000683351.1 )
Associated Disease
myocardial infarction
Source Database
DisGeNET
Description
This study investigates whether the interaction between diuretics and alpha-adducin (ADD1) G460W or G-protein beta3-subunit (GNB3) rs2301339 polymorphism modifies the risk of myocardial infarction (MI) or stroke.
Pubmed
17189961
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0193695189628021
Year of publication
2007
Drugs