Annotation Detail
Information
- Associated Genes
- ERCC2
- Associated Variants
-
ERCC1 c.-8+123G>T
(
ENST00000300853.8,
ENST00000340192.11,
ENST00000423698.6,
ENST00000589165.5 )
ERCC1 c.-8+123G>T ( ENST00000300853.8, ENST00000340192.11, ENST00000423698.6, ENST00000589165.5 ) - Associated Disease
- Carcinoma of lung
- Source Database
- DisGeNET
- Description
- MDR (multifactor dimensionality reduction) analysis demonstrated the best significant model of two-attributes containing smoking duration and rs2298881 in ERCC1 (P=0.004-0.005) and suggested that the effects of high-order interactions among smoking duration and ERCC2, PPP1R13, ERCC1 htSNPs could modulate lung cancer risk.
- Pubmed
- 24140460
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0138435354760955
- Year of publication
- 2013
Drugs