Annotation Detail
Information
- Associated Genes
- ERCC1
- Associated Variants
-
ERCC1 c.-8+123G>T
(
ENST00000300853.8,
ENST00000340192.11,
ENST00000423698.6,
ENST00000589165.5 )
ERCC1 c.-8+123G>T ( ENST00000300853.8, ENST00000340192.11, ENST00000423698.6, ENST00000589165.5 ) - Associated Disease
- prostate carcinoma
- Source Database
- DisGeNET
- Description
- Men carrying the variant A allele at ERCC1 rs2298881 exhibited increased prostate cancer risk with high versus no fonofos use [odds ratio (OR) 2.98; 95% confidence interval (CI) 1.65-5.39; P(interact) = 3.6 × 10(-4); FDR-adjusted P = 0.11].
- Pubmed
- 22102698
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
- Year of publication
- 2012
Drugs