Annotation Detail

Information
Associated Genes
RTEL1
Associated Variants
RTEL1 c.1191+227T>C, RTEL1-TNFRSF6B c.1275+227T>C ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.1191+227T>C, RTEL1-TNFRSF6B c.1275+227T>C ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
Associated Disease
glioblastoma
Source Database
DisGeNET
Description
The opposite is true of RTEL (20q13) region polymorphisms, which are significantly associated with glioblastoma (rs2297440, OR = 0.56, P = 4.6 × 10(-10)) but not oligodendroglial tumor.
Pubmed
21356187
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Year of publication
2011
Drugs