Annotation Detail

Information
Associated Genes
TRIB3
Associated Variants
TRIB3 p.Gln111Arg (p.Q111R) ( ENST00000217233.9, ENST00000422053.3, ENST00000449710.6, ENST00000615226.5, ENST00000714424.1, ENST00000714425.1, ENST00000714426.1, ENST00000714427.1, ENST00000714428.1 )
TRIB3 p.Gln111Arg (p.Q111R) ( ENST00000217233.9, ENST00000422053.3, ENST00000449710.6, ENST00000615226.5, ENST00000714424.1, ENST00000714425.1, ENST00000714426.1, ENST00000714427.1, ENST00000714428.1 )
Associated Disease
myocardial infarction
Source Database
DisGeNET
Description
We have recently described a Q84R gain-of-function polymorphism of TRIB3 with the R84 variant being associated with insulin resistance and an earlier age at myocardial infarction.
Pubmed
18436806
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2008
Drugs