Annotation Detail
Information
- Associated Genes
- INS
- Associated Variants
-
INS c.-23T>A, INS-IGF2 c.-17-6T>A
(
ENST00000397270.1,
ENST00000381330.5,
ENST00000397262.5,
ENST00000250971.7 )
CLEC16A c.2641+18780G>A ( ENST00000703130.1, ENST00000409790.6 )
CTLA4 c.*1148+236G>A
PPDPFL c.*140A>G ( ENST00000303202.8, ENST00000399653.8, ENST00000517663.5, ENST00000522267.6 )
INS c.-23T>A, INS-IGF2 c.-17-6T>A ( ENST00000397270.1, ENST00000250971.7, ENST00000381330.5, ENST00000397262.5 )
CLEC16A c.2641+18780G>A ( ENST00000409790.6, ENST00000703130.1 )
CTLA4 c.*1148+236G>A
PPDPFL c.*140A>G ( ENST00000303202.8, ENST00000399653.8, ENST00000517663.5, ENST00000522267.6 ) - Associated Disease
- Autoimmune thyroid disease
- Source Database
- DisGeNET
- Description
- Furthermore, a joint analysis, with the INS and CTLA4 SNPs, revealed that CTLA4 rs3087243, ERBB3 rs2292399, and CLEC16A rs2903692, but not INS rs689, were significant risk factors for the cooccurrence of AITD in Japanese T1D.
- Pubmed
- 18940880
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
- Year of publication
- 2009
Drugs