Annotation Detail
Information
- Associated Genes
- MTRR
- Associated Variants
-
MTRR p.Ser257Thr (p.S257T)
(
ENST00000264668.6,
ENST00000440940.7 )
MTRR p.Arg415Cys (p.R415C) ( ENST00000264668.6, ENST00000440940.7 )
MTRR p.Ser257Thr (p.S257T) ( ENST00000264668.6, ENST00000440940.7 )
MTRR p.Arg415Cys (p.R415C) ( ENST00000264668.6, ENST00000440940.7 ) - Associated Disease
- Adenoma of large intestine
- Source Database
- DisGeNET
- Description
- In addition, the methionine synthase reductase (MTRR) Arg415Cys and MTRR Ser284Thr variant carriers, also in the vitamin B(12) pathway, have suggestive associations with advanced colorectal adenoma (defined as being larger than 1 cm, villous, tubular-villous or carcinoma in situ histology).
- Pubmed
- 17389618
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2007
Drugs