Annotation Detail

Information
Associated Genes
JAK1
Associated Variants
JAK1 MUTATION
JAK1 MUTATION
Associated Disease
Ki-1+ Anaplastic Large Cell Lymphoma
Source Database
DisGeNET
Description
We identified activating mutations of JAK1 and/or STAT3 genes in ∼20% of 88 [corrected] ALK(-) ALCLs and demonstrated that 38% of systemic ALK(-) ALCLs displayed double lesions.
Pubmed
25873174
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs