Annotation Detail

Information
Associated Genes
FEV
Associated Variants
rs2276109
rs2276109
Associated Disease
asthma
Source Database
DisGeNET
Description
The minor allele (G) of a functional variant in the promoter region of MMP12 (rs2276109 [-82A-->G]) was positively associated with FEV(1) in a combined analysis of children with asthma and adult former and current smokers in all cohorts (P=2x10(-6)).
Pubmed
20018959
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0211724660222637
Year of publication
2009
Drugs