Annotation Detail

Information
Associated Genes
MMP12
Associated Variants
rs2276109
rs2276109
Associated Disease
Heart failure
Source Database
DisGeNET
Description
For MMP12 -82A>G (rs2276109), no pharmacogenetic effect was found for the primary outcome, although lower HRs were observed for AA homozygotes in the chlorthalidone-amlodipine comparison for HF (P = 0.015).
Pubmed
21887284
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2011
Drugs