Annotation Detail
Information
- Associated Genes
- MMP3
- Associated Variants
-
MMP12 INSERTION
MMP12 INSERTION
MMP12 INSERTION
MMP12 INSERTION
rs2276109
rs2276109 - Associated Disease
- Aneurysm
- Source Database
- DisGeNET
- Description
- Analysis of the five MMP genes identified modest trends in allele and genotype frequencies for MMP-3 rs3025058 (-/T) and haplotypes containing MMP-3 rs3025058 (-/T) and MMP-12 rs2276109 (A/G) (nominal P=2 to 4 × 10(-5)) that conferred increased risk of aneurysm formation in US-UK subjects.
- Pubmed
- 20827277
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00399568321108385
- Year of publication
- 2010
Drugs