Annotation Detail
Information
- Associated Genes
- IL17A
- Associated Variants
-
NC_000006.12:g.52186235G>A
NC_000006.12:g.52186235G>A - Associated Disease
- Graft-vs-Host Disease
- Source Database
- DisGeNET
- Description
- When we examined the impact of rs2275913 in a cohort consisting of 438 pairs of patients and their unrelated donors transplanted through the Japan Marrow Donor Program, the donor IL-17 197A allele was found to be associated with a higher risk of acute graft-versus-host disease (GVHD; hazard ratio [HR], 1.46; 95% confidence interval [CI], 1.00 to 2.13; P = 0.05).
- Pubmed
- 22028838
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.120814325616241
- Year of publication
- 2011
Drugs