Annotation Detail
Information
- Associated Genes
- NOS2
- Associated Variants
-
NOS2 MUTATION
NOS2 MUTATION - Associated Disease
- Idiopathic hypereosinophilic syndrome
- Source Database
- DisGeNET
- Description
- After evaluation of secondary causes of eosinophilia, the 2008 World Health Organization establishes a semi-molecular classification scheme of disease subtypes including 'myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1', chronic eosinophilic leukemia, not otherwise specified, (CEL, NOS), lymphocyte-variant hypereosinophilia, and idiopathic hypereosinophilic syndrome (HES), which is a diagnosis of exclusion.
- Pubmed
- 26486351
- Section of the abstract supporting the evidence
- RISK STRATIFICATION
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs