Annotation Detail
Information
- Associated Genes
- IL17A
- Associated Variants
-
NC_000006.12:g.52186235G>A
NC_000006.12:g.52186235G>A - Associated Disease
- Autoimmune Diseases
- Source Database
- DisGeNET
- Description
- These findings substantiate the functional relevance of the rs2275913 polymorphism and indicate that the higher IL-17 secretion by individuals with the 197A allele likely accounts for their increased risk for acute GVHD and certain autoimmune diseases.
- Pubmed
- 22028838
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.13764372168522
- Year of publication
- 2011
Drugs