Annotation Detail

Information
Associated Genes
PLCE1
Associated Variants
PLCE1 p.His1927Arg (p.H1927R) ( ENST00000371375.2, ENST00000371380.8, ENST00000371385.8, ENST00000675218.1, ENST00000688810.1, ENST00000692396.1 )
PLCE1 p.His1927Arg (p.H1927R) ( ENST00000371375.2, ENST00000371380.8, ENST00000371385.8, ENST00000675218.1, ENST00000688810.1, ENST00000692396.1 )
Associated Disease
Malignant neoplasm of esophagus
Source Database
DisGeNET
Description
However, three genome-wide association studies of esophageal cancer have identified a shared susceptibility locus at 10q23 (rs2274223: A5780G) in phospholipase C epsilon 1 (PLCE1).
Pubmed
24127316
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.127719924550087
Year of publication
2013
Drugs