Annotation Detail
Information
- Associated Genes
- MDM2
- Associated Variants
-
MDM2 MUTATION
MDM2 MUTATION - Associated Disease
- Liposarcoma, Dedifferentiated
- Source Database
- DisGeNET
- Description
- Using MLPA, with a cut-off ratio of >2, 36/71 samples (22 atypical lipomatous tumors/well-differentiated liposarcomas, and 14 dedifferentiated liposarcomas) showed MDM2 and CDK4 amplification.
- Pubmed
- 25679065
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,ORPHANET
- DisGENET score for the Gene Disease association
- 0.127600372418248
Drugs