Annotation Detail

Information
Associated Genes
GJB2
Associated Variants
GJB2 p.Val84Leu (p.V84L) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Val84Leu (p.V84L) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Val84Met (p.V84M) ( ENST00000382848.5, ENST00000382844.2 )
GJB2 p.Val84Leu (p.V84L) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Val84Leu (p.V84L) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Val84Met (p.V84M) ( ENST00000382844.2, ENST00000382848.5 )
Associated Disease
Hearing Loss, Mixed Conductive-Sensorineural
Source Database
DisGeNET
Description
This deletion was observed in trans to a GJB2 mutated allele carrying the p.Val84Met (V84M) mutation and was shown to be associated with hearing loss.
Pubmed
19101659
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0646031655551122
Year of publication
2009
Drugs