Annotation Detail
Information
- Associated Genes
- RPL37
- Associated Variants
-
HNF1A c.327-2680C>T
(
ENST00000541395.5,
ENST00000544413.2,
ENST00000400024.6,
ENST00000257555.11 )
HNF1A c.327-1775A>G ( ENST00000544413.2, ENST00000400024.6, ENST00000257555.11, ENST00000541395.5 )
HNF1A p.Leu459= (p.L459=) ( ENST00000541395.5, ENST00000544413.2, ENST00000400024.6, ENST00000257555.11 )
HNF1A p.Ser487Asn (p.S487N) ( ENST00000544413.2, ENST00000541395.5, ENST00000257555.11, ENST00000400024.6 )
HNF1A c.327-2680C>T ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 )
HNF1A c.327-1775A>G ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 )
HNF1A p.Leu459= (p.L459=) ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 )
HNF1A p.Ser487Asn (p.S487N) ( ENST00000257555.11, ENST00000400024.6, ENST00000541395.5, ENST00000544413.2 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- The rs2259820_T (1.14 (1.03-1.26); P = 0.011) and rs2464196_C (1.12 (1.02-1.24); P = 0.024) were associated with type 2 diabetes mellitus (T2DM), while the rs2393791_T (1.14 (1.01-1.28); P = 0.032), rs7310409_G (1.16 (1.03-1.30); P = 0.013), and rs2464196_AG+GG (1.25 (1.05-1.49); P = 0.012) were implicated in hypertension.
- Pubmed
- 25057215
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs