Annotation Detail

Information
Associated Genes
NOS2
Associated Variants
NOS2 MUTATION
NOS2 MUTATION
Associated Disease
Tumor Progression
Source Database
DisGeNET
Description
Interestingly, analysis of genes altered by iNOS-directed shRNA showed that the knockdown of iNOS expression was associated with a significant down-regulation of signalling pathways involved in stemness and tumour progression in colon CSCs.
Pubmed
25875314
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs