Annotation Detail

Information
Associated Genes
MMP1
Associated Variants
MMP1 MUTATION
MMP1 MUTATION
Associated Disease
Tumor Progression
Source Database
DisGeNET
Description
In bladder cancer xenograft models, R3Mab substantially blocked tumor progression and reduced the protein levels of human MMP-1 and pro-MMP-10 in tumor tissues as well as in mouse serum.
Pubmed
25326231
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00380018620912425
Drugs