Annotation Detail

Information
Associated Genes
INS
Associated Variants
KCNQ1 c.1795-11803A>C ( ENST00000713725.1, ENST00000646564.2, ENST00000335475.6, ENST00000155840.12, ENST00000526095.2, ENST00000496887.7 )
KCNQ1 c.1795-11803A>C ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000526095.2, ENST00000646564.2, ENST00000713725.1 )
Associated Disease
gestational diabetes
Source Database
DisGeNET
Description
In the analyses of the GDM-related phenotype, only the risk allele of KCNQ1 rs2237895 was significantly associated with a high-level insulin sensitivity oral glucose tolerance test among patients with GDM (P = 0.0003, 0.004, and 0.05 for codominant, dominant, and recessive models, respectively).
Pubmed
19850681
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0238208713946101
Year of publication
2010
Drugs